AutoGrow: A Novel Algorithm for Protein Inhibitor Design
نویسندگان
چکیده
منابع مشابه
AutoGrow 3.0: an improved algorithm for chemically tractable, semi-automated protein inhibitor design.
We here present an improved version of AutoGrow (version 3.0), an evolutionary algorithm that works in conjunction with existing open-source software to automatically optimize candidate ligands for predicted binding affinity and other druglike properties. Though no substitute for the medicinal chemist, AutoGrow 3.0, unlike its predecessors, attempts to introduce some chemical intuition into the...
متن کاملA Novel Algorithm for Digital Distance Relaying
Distance relays are used to protect EHV and HV Transmission lines. Over the past decades many algorithms have emerged for digital distance relays. These are based on the calculation of the transmission line impedance from the relaying to fault points. In this paper a novel method for digital distance relaying is proposed. In the method the tracking procedure is implemented. The method uses the ...
متن کاملA Novel Algorithm for Digital Distance Relaying
Distance relays are used to protect EHV and HV Transmission lines. Over the past decades many algorithms have emerged for digital distance relays. These are based on the calculation of the transmission line impedance from the relaying to fault points. In this paper a novel method for digital distance relaying is proposed. In the method the tracking procedure is implemented. The method uses the ...
متن کاملA novel heuristic algorithm for capacitated vehicle routing problem
The vehicle routing problem with the capacity constraints was considered in this paper. It is quite difficult to achieve an optimal solution with traditional optimization methods by reason of the high computational complexity for large-scale problems. Consequently, new heuristic or metaheuristic approaches have been developed to solve this problem. In this paper, we constructed a new heuristic ...
متن کاملa novel algorithm for digital distance relaying
distance relays are used to protect ehv and hv transmission lines. over the past decades many algorithms have emerged for digital distance relays. these are based on the calculation of the transmission line impedance from the relaying to fault points. in this paper a novel method for digital distance relaying is proposed. in the method the tracking procedure is implemented. the method uses the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical Biology & Drug Design
سال: 2009
ISSN: 1747-0277,1747-0285
DOI: 10.1111/j.1747-0285.2008.00761.x